|
KMID : 1149120210180010020
|
|
Journal of the Korean Society for Psoriasis
2021 Volume.18 No. 1 p.20 ~ p.23
|
|
|
Three Cases of Biologic Treatment for Psoriasis Patients with Chronic Renal Failure
|
|
Jang Yun-Kyung
Kim Dong-Hyun
|
|
|
Abstract
|
|
|
|
Psoriasis has been associated with various cardiovascular and metabolic comorbidities. Recently, there are studies reporting the association of psoriasis with renal diseases. However, there is little information on the safety and efficacy of biologic therapies used in psoriasis patients with renal failure. A 35-year-old man presented with psoriasis and chronic kidney disease (CKD) undergoing hemodialysis. Narrowband ultraviolet B (NBUVB) therapy was unsatisfactory. After treatment with guselkumab, psoriasis area and severity index (PASI) score decreased from 11 to 1.2 after 12 weeks. A 52- year old-man and a 39-year-old woman presented with psoriasis and CKD. Treatment with NBUVB and methotrexate did not meet the treatment goal. After treatment with ixekizumab, PASI score decreased from 11 to 2 and 12 to 1.4 after 12 weeks, respectively. All of them have maintained good clinical responses without side effects. Herein, we report successful cases of using guselkumab and ixekizumab to treat psoriasis patients with renal failure suggesting guselkumab and ixekizumab as safe treatment options.
|
|
|
KEYWORD
|
|
|
Biologics, Chronic Renal failure, Hemodialysis, Psoriasis
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|